Neil G. Quigley1, Katja Steiger1, Sebastian Hoberück2, Norbert Czech3, Maximilian A. Zierke1, Susanne
Kossatz4, Marc Pretze2, Frauke Richter1, Wilko Weichert1, Christian Pox5, Jörg Kotzerke2, Johannes Notni1, 6
Expression of the TGF-β activating cell adhesion receptor αvβ6-integrin is closely related to cancer malignancy, since it drives invasion and metastasis. αvβ6-integrin is found in high density on tumor cells especially of pancreatic ductal adenocarcinoma (PDAC) , but also squamous cell-, cervical-, lung adeno-, and other carcinomas as well as fibrotic diseases (idiopathic pulmonary fibrosis, IPF). Sensitive probes for clinical imaging of αvβ6-integrin are thus highly desirable.